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Granulocytes1,2

Granulocytes (polymorphonuclear leukocytes) are immune cells which contain enzymes and other substances which destroy microorganisms. Granulocytes, which develop from myeloblasts, are able to move through the bloodstream and into tissues to the site of infection within minutes.

There are three types of granulocytes – neutrophils, basophils, and eosinophils. They are differentiated by the size and color of the granules, as well as by the method of attack. Neutrophils destroy by ingesting the microorganism while eosinophils and basophils target their granules onto harmful cells.

  1. U.S. Department of Health and Human Services. National Institutes of Health. Understanding the Immune System: How It Works. NIH Pub No. 03-5423; p. 15.
  2. Blaese RM, Winkelstein J. Patient & Family Handbook for Primary Immunodeficiency Diseases. Towson, MD: Immune Deficiency Foundation; 2007, p.6.